Journal of Interdisciplinary Histopathology

2019, Vol: 7, Issue: 1

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Case Report

J Interdiscip Histopathol. 2013; 1(3): 168-171

doi: 10.5455/jihp.20130115114630

Retroperitoneal Non-functioning Paraganglioma: A Case Report

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya.

Cited by (2)

Abstract
Retroperitoneal paragangliomas are relatively rare endocrine tumours derived from the extra-adrenal paraganglia of the autonomic nervous system. They can be functional when they secrete catecholamines or non-functional. The diagnosis of a paraganglioma is infrequently made preoperatively unless the tumour is functional. In this paper, the authors report a new case of non-functional paraganglioma. A 54-year-old woman with a past medical history of viral hepatitis, presented with vague abdominal pain of five years' duration. On examination, no abdominal mass was palpable and her blood pressure was 100/60 mm Hg. Abdominal computed tomography scan demonstrated a well-defined hypervascular retroperitoneal mass of heterogeneous density in the left para-aortic region measuring 3cm in diameter. As paraganglioma was suspected preoperatively, serum and urine cathecholamine levels were performed and were within normal range. Complete surgical excision of this mass was performed. Histological examination of the surgical specimen coupled with immunohistochemical study was consistent with the diagnosis of pararganglioma. Retroperitoneal paragangliomas are most commonly benign with good prognosis, but can be locally invasive and metastasize as well. The possibility for malignant transformation of paragangliomas makes surgical excision the treatment of choice.

Key words: paraganglioma, retroperitoneal tumour, non-functioning, immunohistochemistry.

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REFERENCES

Clements RH, Holzman MD, Blevins LS, Molpus K, Goldstein RE. Endoscopic retroperitoneal resection of a para-aortic paraganglioma: Report of a case and description of a technique. Surgery 1999; 126: 977-979. http://dx.doi.org/10.1016/S0039-6060(99)70043-7

http://dx.doi.org/10.1016/S0039-6060(99)70043-7

Wen J, Li HZ, Ji ZG, Mao QZ, Shi BB, Yan WG. A case of large silent extra-adrenal retroperitoneal paraganglioma resected laparoscopically. Chin Med Sci J 2010; 25: 61-64. http://dx.doi.org/10.1016/S1001-9294(10)60023-5

http://dx.doi.org/10.1016/S1001-9294(10)60023-5

Whalen RK, Althausen AF, Daniels GH. Extra-adrenal pheochromocytoma. J Urol 1992; 147:1–10. [Pubmed]    Glenner GG, Grimley PM. Tumors of the extra-adrenal paraganglioma system (including chemoreceptors). In: Atlas of Tumor Pathology, Fascicle 9, Armed Forces Institute of Pathology, Washington DC, USA, 1997.

Enzinger FM, Weiss SW. Soft Tissue Tumors, 2nd ed, Mosby, St Louis, USA, pp 836-840, 1988

Brantigan CO, Katase RY. Clinical and pathologic features of paragangliomas of the organ of Zuckerkandl. Surgery 1969; 65: 898-905. [Pubmed]

Kimura N, Capella C, De Krijger RR, Thompson LDR, Lam KY, Komminoth P, Tischler AS, Young WF. Pathology and Genetics of Tumours of Endocrine Organs, IARC Press, Lyon, Paris, pp164-165, 2004.

Neumann HP, Pawlu C, Peczkowska M, Bausch B, McWhinney SR, Muresan M, Buchta M, Franke G, Klisch J, Bley TA, Hoegerle S, Boedeker CC, Opocher G, Schipper J, Januszewicz A, Eng C. Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD and gene mutations. Journal of the American Medical Association 2004; 292: 943-951. http://dx.doi.org/10.1001/jama.292.8.943 [Pubmed]
http://dx.doi.org/10.1001/jama.292.8.943

Law NW, Alfano L. Non-functioning retroperitoneal paraganglioma. J R Soc Med 1987; 80:246-247. [Pubmed]    [PMC Free Fulltext]

Yang JH, Bae SJ, Park S, Park HK, Jung HS, Chung JH, Min YK, Lee MS, Kim KW, Lee MK. Bilateral pheochromocytoma associated with paraganglioma and papillary thyroid carcinoma: report of an unusual case. Endocrine Journal 2007; 54: 227-231. http://dx.doi.org/10.1507/endocrj.K06-068 [Pubmed]
http://dx.doi.org/10.1507/endocrj.K06-068

Elder EE, Elder G, Larsson C. Pheochromocytoma and functional paraganglioma syndrome: no longer the 10% tumor. Journal of Surgical Oncology 2005; 89: 193-201. http://dx.doi.org/10.1002/jso.20177 [Pubmed]
http://dx.doi.org/10.1002/jso.20177

Mhanna T, Pianta E, Bernard P, Hervieu V, Partensky C. Preaortic paraganglioma mimicking a hypervascular tumor of the pancreas. Hepato-Gastroenterology 2004; 51: 1198-1201. [Pubmed]

Rha SE, Byun JY, Jung SE, Chun HJ, Lee HG, Lee JM. Neurogenic tumors in the abdomen: tumor types and imaging characteristics. Radiographics 2003; 23: 29-43. http://dx.doi.org/10.1148/rg.231025050 [Pubmed]
http://dx.doi.org/10.1148/rg.231025050

Tonyukuk V, Emral R, Temizkan S, Sertçelik A, Erden I, Corapçioglu D. Patient with multiple paraganglioma treated with long acting somatostatin analogue. Endocrine Journal 2003; 50: 507-513. http://dx.doi.org/10.1507/endocrj.50.507 [Pubmed]
http://dx.doi.org/10.1507/endocrj.50.507

This Article Cited By the following articles

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Pancreatic paraganglioma - a rare and dangerous entity. Vascular anatomy and impact on management Journal of Surgical Case Reports 2014; 2014(7): rju074.	2

How to Cite this Article

Pubmed Style

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya. Retroperitoneal Non-functioning Paraganglioma: A Case Report. J Interdiscip Histopathol. 2013; 1(3): 168-171. doi:10.5455/jihp.20130115114630

Web Style

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya. Retroperitoneal Non-functioning Paraganglioma: A Case Report. http://www.ejmjih.com/?mno=31315 [Access: October 15, 2019]. doi:10.5455/jihp.20130115114630

AMA (American Medical Association) Style

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya. Retroperitoneal Non-functioning Paraganglioma: A Case Report. J Interdiscip Histopathol. 2013; 1(3): 168-171. doi:10.5455/jihp.20130115114630

Vancouver/ICMJE Style

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya. Retroperitoneal Non-functioning Paraganglioma: A Case Report. J Interdiscip Histopathol. (2013), [cited October 15, 2019]; 1(3): 168-171. doi:10.5455/jihp.20130115114630

Harvard Style

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya (2013) Retroperitoneal Non-functioning Paraganglioma: A Case Report. J Interdiscip Histopathol, 1 (3), 168-171. doi:10.5455/jihp.20130115114630

Turabian Style

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya. 2013. Retroperitoneal Non-functioning Paraganglioma: A Case Report. Journal of Interdisciplinary Histopathology, 1 (3), 168-171. doi:10.5455/jihp.20130115114630

Chicago Style

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya. "Retroperitoneal Non-functioning Paraganglioma: A Case Report." Journal of Interdisciplinary Histopathology 1 (2013), 168-171. doi:10.5455/jihp.20130115114630

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Faten Limaiem, Saadia Bouraoui, Sirine Bouslama, Sana Ben Slama, Ahlem Lahmar, Sabeh Mzabi-Regaya (2013) Retroperitoneal Non-functioning Paraganglioma: A Case Report. Journal of Interdisciplinary Histopathology, 1 (3), 168-171. doi:10.5455/jihp.20130115114630

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