Effects of Administration of Melatonin on the Harderian Gland of Sheep

Abstract

Enas A.Abd El Hafez, Alaa Sayed Abou-Elhamd and Ahmed Hassan S. Hassan

Objective: The aim of this study was to examine the morphological structure of the harderian gland of sheep by using light and electron microscopy, and the effect of melatonin administration on the secretory activity of the gland. Methods: This experiment was performed on fifteen Soay rams aged 1.5 years. Histochemical studies were performed by using PAS (Periodic acid Schiff), alcian blue and alcian blue/PAS. Results: Presented study revealed that the harderian gland of sheep was of compound tubuloalveolar type. By using light microscopy, the secretory end-pieces of the harderian gland of sheep were lined with principal and basal cells. The principal cells showed different secretory activities. Conclusions: This study presents the first histological and ultrastructural features of the harderian gland in sheep. After melatonin administration, the PAS and alcian blue reactivity in the epithelial lining of the harderian gland was increased. In addition, the epithelial lining of the harderian gland of sheep accumulate more lipid vacuoles.

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