Gary Clayman
The Hospital for Endocrine Surgery, The Thyroid Institute, Tampa, FL, USAPublications
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Mini Review
Human Amnion/Chorion Membrane Use During Neck Surgery to Protect the Recurrent Laryngeal Nerve
Author(s): Gary Clayman*, Rashmi Roy and Nathaniel Walsh
Recurrent Laryngeal Nerve (RLN) damage is a significant and prevalent complication of neck surgery of all types. Based on the beneficial role of Human Amnion/Chorion Membrane (HACM) allograft in wound management and nerve regeneration, we investigated whether placement of a commercially available HACM allograft on dissected RLN during thyroidectomy could reduce the occurrence and/or duration of RLN. Preliminary studies in 100 dissected nerves showed benefit in both occurrence and duration, so the study was increased to 1000 consecutive at-risk nerves (dissected exposure of at least 3 cm of RLN) in 670 patients which received HACM directly onto the nerves prior to wound closure. 2000 at-risk nerves without HACM in 1420 matched patients served as controls. All operations were performed by the same surgeons using nerve monitoring endotracheal tub.. Read More»